Erik I Christensen Selected Research

intrinsic factor-cobalamin receptor

1/2021	A well-developed endolysosomal system reflects protein reabsorption in segment 1 and 2 of rat proximal tubules.
5/2016	Tubular proteinuria in patients with HNF1α mutations: HNF1α drives endocytosis in the proximal tubule.
11/2013	Increased lysosomal proteolysis counteracts protein accumulation in the proximal tubule during focal segmental glomerulosclerosis.
11/2010	Cubilin is essential for albumin reabsorption in the renal proximal tubule.
8/2010	The effect of progressive glomerular disease on megalin-mediated endocytosis in the kidney.
6/2008	Urinary protein excretion pattern and renal expression of megalin and cubilin in nephropathic cystinosis.
7/2004	Protein reabsorption in renal proximal tubule-function and dysfunction in kidney pathophysiology.
2/2002	Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin.

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Erik I Christensen Research Topics

Disease

13	Proteinuria 01/2021 - 03/2004
5	Fabry Disease (Fabry's Disease) 03/2014 - 03/2007
4	Donnai-Barrow syndrome 01/2019 - 03/2013
3	Fanconi Syndrome (Syndrome, Fanconi) 01/2021 - 06/2008
3	Albuminuria 01/2021 - 11/2010
3	Fibrosis (Cirrhosis) 03/2017 - 06/2010
3	Inflammation (Inflammations) 03/2017 - 11/2013
2	Disease Progression 11/2019 - 03/2017
2	Cystinosis 11/2019 - 06/2008
2	Myopia 01/2019 - 10/2014
2	Pathologic Processes 01/2017 - 10/2003
2	Carcinoma (Carcinomatosis) 10/2014 - 03/2010
2	Chronic Kidney Failure (Chronic Renal Failure) 03/2014 - 03/2007
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 11/2019
1	Retinal Degeneration 01/2019
1	Kidney Calculi (Kidney Stone) 10/2018
1	Hypercalciuria 10/2018
1	Alcoholic Fatty Liver 03/2017
1	Fatty Liver 03/2017
1	Non-alcoholic Fatty Liver Disease 03/2017
1	Ovarian Neoplasms (Ovarian Cancer) 02/2017
1	Fibrosarcoma 01/2017
1	Pseudoxanthoma Elasticum (Gronblad Strandberg Syndrome) 12/2016
1	Neoplasms (Cancer) 10/2014
1	Lymphatic Metastasis 10/2014
1	Kidney Diseases (Kidney Disease) 01/2014
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 11/2013
1	Renal Tubular Acidosis (Distal Renal Tubular Acidosis) 02/2013
1	Acidosis 02/2013
1	Parkinson Disease (Parkinson's Disease) 01/2013
1	Collagen Diseases (Collagen Disease) 08/2010
1	Hereditary Nephritis (Alport Syndrome) 08/2010
1	Autosomal Recessive 3 Severe Congenital Neutropenia 05/2007
1	Cyclic neutropenia 05/2007
1	Neutropenia 05/2007
1	Infections 04/2007
1	Reperfusion Injury 04/2005
1	Imerslund-Grasbeck syndrome 03/2004
1	Acute Kidney Injury (Acute Renal Failure) 09/2003
1	Myoglobinuria 09/2003

Drug/Important Bio-Agent (IBA)

13	Low Density Lipoprotein Receptor-Related Protein-2IBA 01/2021 - 07/2004
10	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2003
8	intrinsic factor-cobalamin receptorIBA 01/2021 - 02/2002
6	AlbuminsIBA 01/2021 - 06/2008
4	globotriaosylceramide (globotriosylceramide)IBA 03/2014 - 03/2007
3	GalactosidasesIBA 03/2014 - 01/2011
2	SodiumIBA 01/2021 - 10/2018
2	Cystine (L-Cystine)IBA 11/2019 - 06/2008
2	Messenger RNA (mRNA)IBA 02/2017 - 11/2013
2	Hemoglobins (Hemoglobin)IBA 02/2015 - 02/2002
2	LigandsIBA 11/2013 - 08/2010
1	Cysteamine (Mercaptamine)FDA Link 11/2019
1	Blood Proteins (Serum Proteins)IBA 11/2019
1	DisulfidesIBA 11/2019
1	CalciumIBA 10/2018
1	Furosemide (Lasix)FDA LinkGeneric 10/2018
1	Sodium Chloride FDA LinkGeneric 10/2018
1	UromodulinIBA 10/2018
1	CarbohydratesIBA 03/2017
1	FructoseIBA 03/2017
1	EndotoxinsIBA 03/2017
1	GlucocorticoidsIBA 03/2017
1	GlycogenIBA 03/2017
1	Immunoconjugates (Immunoconjugate)IBA 03/2017
1	Enzyme Precursors (Zymogens)IBA 01/2017
1	Tissue Inhibitor of MetalloproteinasesIBA 01/2017
1	Tissue Inhibitor of Metalloproteinase-2IBA 01/2017
1	Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)IBA 01/2017
1	EnzymesIBA 01/2017
1	Carrier Proteins (Binding Protein)IBA 12/2016
1	Scavenger Receptors (Scavenger Receptor)IBA 02/2015
1	MicroRNAs (MicroRNA)IBA 10/2014
1	RNA (Ribonucleic Acid)IBA 10/2014
1	GlycosphingolipidsIBA 03/2014
1	ChitosanIBA 01/2014
1	AmmoniaIBA 02/2013
1	dirhodium tetraacetate (DRTA)IBA 02/2013
1	AcidsIBA 02/2013
1	Nerve Growth Factors (Neurotrophins)IBA 01/2013
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 01/2013
1	Recombinant ProteinsIBA 01/2012
1	sortilinIBA 01/2012
1	Connective Tissue Growth FactorIBA 06/2010
1	rat Ybx3 proteinIBA 03/2010
1	Differentiation AntigensIBA 03/2010
1	Immunoglobulin G (IgG)IBA 06/2008
1	Leukocyte Elastase (Neutrophil Elastase)IBA 05/2007
1	serglycinIBA 05/2007
1	GelatinasesIBA 04/2007
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2007
1	OrnithineIBA 04/2007
1	alpha-Galactosidase (Beano)IBA 03/2007
1	IronIBA 04/2005
1	Hemeproteins (Heme Protein)IBA 04/2005
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 03/2004
1	Transforming Growth Factors (Transforming Growth Factor)IBA 10/2003
1	CytokinesIBA 10/2003
1	MyoglobinIBA 09/2003

Therapy/Procedure

2	Enzyme Replacement Therapy 03/2014 - 01/2012
1	Therapeutics 03/2017